Glutamate N-acetyltransferase

In enzymology, a glutamate N-acetyltransferase is an enzyme that catalyzes the chemical reaction


 * N2-acetyl-L-ornithine + L-glutamate $$\rightleftharpoons$$ L-ornithine + N-acetyl-L-glutamate

Thus, the two substrates of this enzyme are N2-acetyl-L-ornithine and L-glutamate, whereas its two products are L-ornithine and N-acetyl-L-glutamate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is N2-acetyl-L-ornithine:L-glutamate N-acetyltransferase. This enzyme participates in the urea cycle and metabolism of amino groups.

Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes, , , and.