House at 115 South Main Street

House at 115 South Main Street is a historic home located at Canastota in Madison County, New York. It was built in the mid-1850s and remodeled in the 1880s in the Queen Anne and Eastlake styles. It is a modest $1 1/2$-story structure surmounted by a multi-gabled roof, which is pierced by a $2 1/2$-story tower.

It was added to the National Register of Historic Places in 1986.