Isaac Caldwell

Isaac Caldwell (1795 – January 12, 1836) was a justice of the Supreme Court of Mississippi from 1825 to 1826.

Born in Clinton, Mississippi, Caldwell became well-known as an attorney. In 1829, Caldwell fought a duel with state legislator John R. Peyton over the latter's vote preventing Caldwell's hometown from being named capital of Mississippi; neither participant was injured. Caldwell was the law partner of Senator George Poindexter, and following Poindexter's defeat in his 1836 bid for reelection, Caldwell ended up engaging in a duel with one of Poindexter's political opponents, Colonel Samuel Gwin. The parties fought with pistols, and "[b]oth parties fell. Caldwell expired in two hours. Gwin was shot through the lungs and survived about a year".