Isaac H. Smith Jr. House

Isaac H. Smith Jr. House is a historic home located at New Bern, Craven County, North Carolina. It was built between 1923 and 1924, and is a two-story American Craftsman style frame dwelling with a brick basement and small attic story. It was the home of Isaac H. Smith Jr. (1899–1953), one of New Bern's most financially successful African-American businessmen.

It was listed on the National Register of Historic Places in 2002.