James Chambers

James Chambers may refer to:


 * James Chambers (pastoralist) (1811–1862), South Australian colonist
 * James Chambers (politician) (1863–1917), Irish lawyer and Unionist
 * James Chambers (English footballer) (born 1980), retired football player
 * James Chambers (Irish footballer) (born 1987), retired football player
 * James Chambers (horn player) (1920–1989), American musician
 * James Cox Chambers (born 1950s), American billionaire heir
 * James Cox Chambers Jr., son of the above, known as Fergie Chambers
 * James Chambers, English musician with Bob Kerr's Whoopee Band
 * James Chambers (born 1948), commonly known as Jimmy Cliff, Jamaican reggae musician
 * James S. Chambers (publisher) (1821–1904), American publisher of the Philadelphia Bulletin
 * USS James S. Chambers, schooner named for the publisher
 * James S. Chambers (editor) (1853–1923), American editor of Public Ledger and grandfather of Whittaker Chambers
 * James Chambers (writer) (born 1970), American author and comic book writer
 * James F. Chambers Jr., (1913–2006), American newspaperman