John M. Sedivy

John Michael Sedivy is the Hermon C. Bumpus Professor of Biology and a professor of Medical Science at Brown University. He is listed as a F1000 Prime faculty member and on Who's Who in Gerontology. He has published over 130 original articles.

He wrote the first book on gene targeting in 1992. In 2006, he published the first comprehensive in vivo quantification of cellular senescence in aging primates. That year, his lab also discovered how (through the Polycomb pathway) c-Myc contributes to the regulation of chromatin states. His research has found that mice missing one copy of the Myc transcription factor live longer than wild-type mice.

He is co-Editor-in-Chief of the journal Aging Cell, and is chair of the 2015 Gordon Research Conference on the Biology of Aging.

Books

 * Sedivy, J. M., & Joyner, A. L. (1992). Gene targeting. WH Freeman and company. ISBN 9780195099683

Selected publications

 * Sedivy, J. M., & Sharp, P. A. (1989). Positive genetic selection for gene disruption in mammalian cells by homologous recombination. Proceedings of the National Academy of Sciences, 86(1), 227–231.

Awards

 * 1974	Ontario Scholar
 * 1981	Ryan Foundation Fellow
 * 1989	March of Dimes Basil O'Connor Starter Scholar
 * 1990	Presidential Young Investigator
 * 1991	Andrew Mellon Award
 * 2006	Hermon C. Bumpus Endowed Chair in Biology, Brown University
 * 2007	Senior Research Scholar in Aging, Ellison Medical Foundation
 * 2009	NIH MERIT Award, National Institute on Aging
 * 2011	Glenn Award for Research in Biological Mechanisms of Aging
 * 2015	Chair, Gordon Research Conference on the Biology of Aging