La Serena

La Serena may refer to:

Places

 * La Serena, Chile
 * La Serena, Colombia
 * La Serena, Spain
 * La Serena, winter home of William Jennings Bryan in Coconut Grove, Miami, Florida

Other uses

 * La Serena (cheese)
 * Deportes La Serena, a football club based in La Serena, Chile