List of Billboard Hot 100 number ones of 1966

These are the Billboard magazine Hot 100 number one hits of 1966.

That year, 16 acts achieved their first number one song, such as Simon & Garfunkel, Lou Christie, Nancy Sinatra, SSgt. Barry Sadler, the Young Rascals, the Mamas & the Papas, Percy Sledge, Tommy James & the Shondells, the Troggs, the Lovin' Spoonful, Donovan, the Association, ? and the Mysterians, the Monkees, Johnny Rivers, and the New Vaudeville Band. Frank Sinatra, having already hit number one before the creation of the Hot 100, earns his first one on the chart. The Beatles, the Supremes and the Monkees are the only acts to hit number one with more than one song, with each of them having two.