List of Coronavirus live isolates

This article aims at keeping an up-to-date list of Coronavirus strains and subspecies successfully isolated and cultured in laboratory, a task which is often challenging. When relevant it shall include a few synthetic chimera as well as some strains that were only propagated in laboratory animals.

Alphacoronavirus

 * 229E
 * NL63
 * GX P2V
 * PEDV (adding Trypsin to Vero cells), propagated in piglets, repeated passage in Vero cells, using Vero/TMPRSS2 and Vero/MSPL cells
 * SADS

Tegacovirus

 * TGEV PRCV
 * Feline coronavirus
 * Canine coronavirus.
 * A recent recombinant CCoV-HuPn-2018 including a human case

Merbecovirus

 * HKU5 SARS-S chimera
 * HKU5 and a MERS PDF-2180-S chimera, with trypsin
 * Various MERS HKU4-RBD chimera
 * HKU4
 * MERS
 * HKU4-like Pangolin Coronavirus

Embecovirus

 * Bovine coronavirus
 * Rabbit HKU14
 * MHV
 * OC43 (1967)
 * HKU1
 * Parker rat coronavirus
 * Dromedary camel HKU23
 * Canine respiratory coronavirus (CRCoV)
 * Equine coronavirus

Sarbecovirus

 * SARS
 * HKU3 SARS-RBD synthetic recombinant
 * bat-SL-CoV ZC45 (in suckling rats)
 * WIV1
 * RsSHC014 (synthetic clone)
 * WIV16
 * WIV1 Rs4874-S synthetic chimera
 * Rs4874 and two synthetic chimera WIV1 Rs7237-S and WIV1 Rs4231-S
 * SARS-CoV-2
 * BANAL-236
 * Pangolin Guangxi P2V
 * Rco319, Rc-os20, Rc-mk2, Rc-kw8 (in Vero with Rc-ACE2)
 * WIV1 Rs4081-S synthetic chimera (with trypsin). In the spike it is a member of clade 2 (including HKU3).
 * WIV1 RsSHC014-S1 chimera
 * Two clade 1 viruses (using ACE2) RsYN2012 and RsYN2016 and one clade 2 virus (not using ACE2) RsHuB2019 in Huh7 cells with trypsin.
 * pangolin/Guangdong, in Vero cells, human organoids, hACE2 mice, hamsters

Gammacoronavirus

 * Avian coronavirus (IBV)
 * Turkey coronavirus

Deltacoronavirus

 * Porcine deltacoronavirus HKU15 including a human case
 * Parrot coronavirus