List of Serie A players with 100 or more goals

This is a list of players who scored over 100 goals in Serie A, Italy's top flight football league, during its history starting from the 1929–30 season. Giuseppe Meazza was the first player to reach both 100 and 200 goals in Serie A. Since the 1948–49 Serie A season, Silvio Piola has headed the list. Goran Pandev was the oldest player to reach the hundred goal milestone at the age of 37 years 268 days. The most recent player to score their hundredth goal in Serie A was Lautaro Martínez in February 2024.

Serie A players with 100 or more goals
Key
 * Bold shows players still playing in Serie A.
 * Italics show players still playing professional football in other leagues.
 * This list does not include goals scored during 1944 Campionato Alta Italia and the 1945–46 Serie A-B.

Most Serie A goals by club
Current Serie A clubs and players are shown in bold. .