List of adverse effects of nilotinib

This is a list of adverse effects of the anti-cancer drug nilotinib, sorted by frequency of occurrence.

Very common
Very common (>10% incidence) adverse effects include:


 * Headache
 * Nausea
 * Hypophosphataemia
 * Hyperbilirubinaemia
 * Alanine aminotransferase (ALT) increased
 * Aspartate aminotransferase increased
 * Lipase increased
 * Rash
 * Itchiness
 * Hair loss
 * Dry skin
 * Muscle aches
 * Fatigue

Common
Common (1–10% incidence) adverse effects include:


 * Constipation
 * Diarrhoea
 * Vomiting
 * Upper abdominal pain
 * Indigestion
 * Joint pain
 * Muscle spasms
 * Pain in extremities
 * Asthenia
 * Peripheral oedema
 * Folliculitis
 * Upper respiratory tract infection (including pharyngitis, nasopharyngitis, rhinitis)
 * Skin papilloma
 * Eosinophilia
 * Lymphopenia
 * Insomnia
 * Anxiety
 * Depression
 * Diabetes mellitus
 * Hypercholesterolaemia
 * Hyperlipidaemia
 * Hypertriglyceridaemia
 * Hyperglycaemia
 * Loss of appetite
 * Dizziness
 * Hypoaesthesia
 * Peripheral neuropathy
 * Eye pruritus
 * Conjunctivitis
 * Dry eye (including xerophthalmia)
 * Vertigo
 * Flushing
 * Hypertension
 * Angina pectoris
 * Arrhythmia (including atrioventricular block, tachycardia, atrial fibrillation, ventricular extrasystoles, bradycardia)
 * QT interval prolonged
 * Palpitations
 * Cough
 * Dyspnoea
 * Abdominal distension
 * Abdominal discomfort
 * Taste changes
 * Flatulence
 * Abnormal liver function
 * Bone pain
 * Back pain
 * Erythema
 * Hyperhidrosis
 * Contusion
 * Acne
 * Dermatitis (including allergic, exfoliative and acneiform)
 * Night sweats
 * Fever without an infectious cause
 * Chest pain (including non-cardiac chest pain)
 * Chest discomfort
 * Decreased haemoglobin
 * Increased blood amylase
 * Increased blood alkaline phosphatase
 * Gamma-glutamyltransferase increased
 * Weight increased
 * Increased blood insulin
 * Increased lipoprotein (including very low density and high density)

Uncommon
Uncommon (0.1–1% incidence) adverse effects include:


 * Arteriosclerosis
 * Bone marrow suppression
 * Both increases and decreases of potassium levels
 * Body temperature change sensation (both hot and cold)
 * Chills
 * Cognitive deficits
 * Conjunctival bleeding and redness
 * Cyanosis
 * Dental sensitivity to pain
 * Bleeding into the lungs
 * Increased blood cholesterol and lipid levels
 * Dystonia
 * Erectile dysfunction
 * Eyelid swelling
 * Flank pain
 * Gastritis
 * Gout
 * Decreased calcium levels
 * Jaundice
 * Malaise
 * Migraine
 * Muscle pain and weakness
 * Pancreatitis
 * Paraesthesia
 * Peripheral arterial occlusive disease
 * Photopsia
 * Pleural effusion
 * Skin eruptions
 * Skin pain
 * Decreased globulins