List of colleges and universities in Pennsylvania

The following is a list of colleges and universities in the U.S. state of Pennsylvania.

Among public institutions, the Commonwealth System of Higher Education includes semi-public state-related colleges and universities. The Pennsylvania State System of Higher Education consists of state-owned master's level institutions.

Defunct institutions
Includes all not-for-profit schools that have closed since 1960.
 * Allegheny University of the Health Sciences (1994–2002) – formed via a merger of Hahnemann Medical College and The Medical College of Pennsylvania; now a part of Drexel University College of Medicine
 * Alliance College (1948–1987) – baccalaureate university in Cambridge Springs (Crawford County)
 * Combs College of Music (1885–1990) – master's music school in Philadelphia
 * Crozer Theological Seminary (1857–1970) – Baptist seminary in Upland (Delaware County)
 * Dropsie College (1907–1986) – graduate school of Jewish studies; merged with the University of Pennsylvania to become the Center for Advanced Judaic Studies
 * Hahnemann Medical College (1849–1994) – merged with The Medical College of Pennsylvania; now a part of Drexel University College of Medicine
 * Hershey Junior College (1938–1965) – associate's college in Derry Township (Dauphin County)
 * Mary Immaculate Seminary (1939–1990) – Roman Catholic seminary in Lehigh Township (Northampton County)
 * Northeastern Christian Junior College (1957–1993) – Bible college affiliated with the Churches of Christ, located in Lower Merion Township (Montgomery County)
 * Medical College of Pennsylvania (1850–1994) – merged with Hahnemann Medical College; now a part of Drexel University College of Medicine
 * Penn Hall Junior College (1906–1973) – associate's college in Chambersburg
 * Pennsylvania College of Podiatric Medicine (1963–1998) – merged with Temple University to become the Temple University School of Podiatric Medicine
 * Philadelphia University (1884–2017) - merged with Thomas Jefferson University
 * Pinebrook Junior College (1914–1992) – nondenominational Bible college in Coopersburg (Lehigh County)
 * Saint Fidelis Seminary (1877–1979) – baccalaureate Roman Catholic university in Summit Township (Butler County)
 * Saint Pius X Seminary (1967–2004) – Roman Catholic seminary in Dalton
 * Spring Garden College (1851–1992) – baccalaureate university in Philadelphia
 * United Wesleyan College (1921–1990) – Bible college affiliated with the Wesleyan Church, located in Allentown
 * Villa Marie College (1925–1989) – baccalaureate Roman Catholic university in Erie; merged with Gannon University