Littleton Female College

Littleton Female College, established as Central Institute and also known as Littleton College, was a Methodist-affiliated women's college Littleton, North Carolina from 1882–1919. James Manly Rhodes (1850–1941) served as its president except for during a two-year period. It was destroyed by a fire in 1919.

Courses included chemistry, physics, stenography, languages, and history. "Female" was dropped from the name in 1912. A historical marker commemorates its history.