Lose

Lose may refer to:


 * Lose (Cymbals Eat Guitars album), the third studio album by American indie rock band Cymbals Eat Guitars
 * "Lose" (song), by KSI and Lil Wayne, 2021
 * "Lose", a song by Travis Scott from his 2016 album Birds in the Trap Sing McKnight
 * League of Super Evil, a Canadian animated television series produced by Nerd Corps Entertainment in conjunction with YTV
 * Lightweight Oxygen Swimmers Equipment, a diving rebreather formerly made by Siebe Gorman, similar to a Swimmer Canoeist's Breathing Apparatus