MC2

MC2 may refer to:


 * Maison de la Culture de Grenoble, a venue for performances in Grenoble, France
 * Marvel Comics 2 is an imprint from Marvel Comics whose comic books depict an alternative future timeline for the Marvel Universe
 * E = mc² is the equation for mass-energy equivalence
 * Microids, a French software company formerly known as MC2-Microïds and later just MC2
 * MC2, an alternate symbol for ACTH receptor
 * Midnight Club 2 a street racing game released in 2003.
 * Project Mc2