MED6

Mediator of RNA polymerase II transcription subunit 6 is one of the subunits of the Mediator complex. It is an enzyme that in humans is encoded by the MED6 gene.

Protein family
This family of proteins represent the transcriptional mediator protein subunit 6 that is required for activation of many RNA polymerase II promoters and which are conserved from yeast to humans.

Interactions
MED6 has been shown to interact with:
 * Cyclin-dependent kinase 8,
 * Estrogen receptor alpha,
 * MED21, and
 * Thyroid hormone receptor alpha.