Microvascular occlusion

Microvascular occlusion refers to conditions that can present with retiform purpura. It has been suggested that phenylephrine may be a cause.

Signs and symptoms
Microvascular occlusions appears as bland necrosis without inflammation and retiform purpura.

Causes
Microvascular occlusions can be caused by heparin-induced thrombocytopenia, cryoglobulinemia, angioinvasive organisms, embolization, disseminated intravascular coagulation, livedoid vasculopathy, cell occlusion syndromes, and iatrogenic causes.

Outlook
The outcomes of microvascular occlusions are usually influenced by the degree, length, nature of the underlying cause, and prompt and effective treatment.