Myotubularin

Myotubularin domain represents a region within eukaryotic myotubularin-related proteins that is sometimes found with the GRAM domain. Myotubularin is a dual-specific lipid phosphatase that dephosphorylates phosphatidylinositol 3-phosphate and phosphatidylinositol (3,5)-bi-phosphate. Mutations in gene encoding myotubularin-related proteins have been associated with disease.

Human proteins containing this domain
MTM1;     MTMR1;     MTMR2;     MTMR3;     MTMR4; MTMR6;    MTMR7;     MTMR8;     MTMR9;     MTMR10;    MTMR11;    MTMR12;    MTMR14;    SBF1;      SBF2;