NADPH dehydrogenase

In enzymology, a NADPH dehydrogenase is an enzyme that catalyzes the chemical reaction


 * NADPH + H+ + acceptor $$\rightleftharpoons$$ NADP+ + reduced acceptor

The 3 substrates of this enzyme are NADPH, H+, and acceptor, whereas its two products are NADP+ and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on NADH or NADPH with other acceptors. It has 2 cofactors: FAD, and FMN.

Nomenclature
The systematic name of this enzyme class is NADPH:acceptor oxidoreductase. Other names in common use include


 * NADPH2 diaphorase
 * NADPH diaphorase
 * old yellow enzyme
 * diaphorase
 * dihydronicotinamide adenine dinucleotide phosphate dehydrogenase
 * NADPH-dehydrogenase
 * NADPH-diaphorase
 * NADPH2-dehydrogenase
 * reduced nicotinamide adenine dinucleotide phosphate dehydrogenase
 * TPNH dehydrogenase
 * TPNH-diaphorase
 * triphosphopyridine diaphorase
 * triphosphopyridine nucleotide diaphorase
 * NADPH2 dehydrogenase
 * NADPH:(acceptor) oxidoreductase.