Piskacek's sign

In medicine, Piskaçek's sign is a physical indication of pregnancy.

It is defined as asymmetry of the enlarged uterus, palpable during pelvic examination, after the first few weeks of pregnancy. It is attributed to lateral implantation of the embryo, which can enlarge one uterine horn before the other. It has also been described as focal softening of the uterus, contrasted to the firmness of the area where the placenta is implanted.

It is named after obstetrician Ludwig Piskaçek, who described it in Vienna in 1899, though it had already been noted by Robert Latou Dickinson of New York in 1892. A similar physical sign had been described by Carl von Fernwald Braun. It comes from an era when laboratory tests for pregnancy had not been developed, but experience gained in pelvic examination during early pregnancy by western gynecologists led them to publish their physical findings, allowing clinical diagnosis of pregnancy. Other such signs of early pregnancy include Goodell, Hegar, Hartman and Chadwick signs.