Premio Lo Nuestro 2021

The 33rd Lo Nuestro Awards ceremony, presented and televised by American television network Univision and Las Estrellas, will recognize the most popular Spanish-language music of 2020 that was played on Uforia Audio Network during the year in 35 categories. The ceremony was held on February 18, 2021, at the American Airlines Arena in Miami.

Performers
Below is the list of the live performances of the artists and the songs they performed:

Winners and nominees
The nominees for the 33rd Lo Nuestro Awards were announced digitally on January 12, 2021, by Univision.

Special Merit Awards

 * Trajectory Award: Gloria Trevi
 * Musical Legacy Award: Los Ángeles Azules
 * Excellence Award: Wisin