Prickle

Prickle may refer to:
 * Thorns, spines, and prickles, a sharp, needle-like structures
 * Prickle cell of the skin
 * Prickle (protein), a planar cell polarity protein
 * The collective noun for a pack of porcupines
 * Prickle (Gumby character), a character on The Gumby Show