Pro-opiomelanocortin converting enzyme

Pro-opiomelanocortin converting enzyme (, prohormone converting enzyme, pro-opiomelanocortin-converting enzyme, proopiomelanocortin proteinase, PCE) is an enzyme. This enzyme catalyses the following chemical reaction


 * Cleavage at paired basic residues in certain prohormones, either between them, or on the carboxyl side

This membrane-bound enzyme is isolated from cattle pituitary secretory vesicle.