Saiyuki Reload: Zeroin

Saiyuki Reload: Zeroin (最遊記RELOAD -ZEROIN-) is a remake to Saiyuki Reload Gunlock and the fifth season of the Saiyuki anime television series adapted from the manga of Saiyuki Reload by Kazuya Minekura and produced by Liden Films.

Saiyuki Reload: Zeroin, will cover the manga's "Even a Worm" arc. For a long time, humans and youkai have learned to coexist in peace within Shangri-La, the earthly paradise. However, under the influence of powerful negative waves generated by mysterious black magic, the youkai became bloodthirsty monsters and started attacking and devouring humans. This dangerous magic is used for a particularly dark purpose: to resurrect Gyumaoh, the Bull Demon King. In order to thwart this plan and to save humanity from violent slaughter, the goddess Kanzeon Bosatsu decides to send Genjo Sanzo and his three disciples: Son Goku, Sha Gojyo and Cho Hakkai, to the west, in the hope that they prevent Gyumaoh from rising once again.

It is directed by Misato Takada, with Michiko Yokote and Aya Matsui writing the series' scripts, Noriko Ogura designing the characters and serving as chief animation director, and Yūsuke Shirato composing the music. The main cast members reprised their roles. It aired from January 6 to March 31, 2022, on AT-X, Tokyo MX1, BS11 consist of 13 episodes.

Sentai Filmworks licensed the series outside of Asia with HIDIVE streaming the series. In South and Southeast Asia, Muse Communication licensed the anime.

The series was released in two Blu-ray box volumes. Volume 1 was released on April 27, 2022 and volume 2 was released on June 29, 2022.

On December 15, 2022, Sentai Filmworks licensed the anime in Northern America and SECTION23 will be the home video distributor which releases on March 7, 2023.

Granrodeo performed the opening theme "Kamino Hotokemo," while Shugo Nakamura performed the ending theme "Ruten."

Reception
Saiyuki Reload: Zeroin series ranked 18th on Filmarks website's poll of top 20 "must see anime of winter 2022." Chris beveridge of The Fandom Post likes the look of the show because of the better color clarity and the depiction of the 2004 anime design.