Sergio Peña

Sergio Peña or Sérgio Pena may refer to:
 * Sergio Peña (Peruvian footballer) (born 1995), Peruvian football midfielder
 * Sergio Peña (Honduran footballer) (born 1987), Honduran football midfielder
 * Sergio Peña (racing driver) (born 1993), American NASCAR driver
 * Sergio Peña Clos (1927–2018), Puerto Rican politician
 * Sérgio Pena (geneticist), Brazilian human geneticist and professor