Sixtus

Sixtus is a Roman name, a corruption of the Greek name "Ξυστος", meaning "polished", and originally Latinized "Xystus". Its Spanish form is Sixto.

Popes

 * Pope Sixtus I (115/116–125)
 * Pope Sixtus II (257–258)
 * Pope Sixtus III (432–440)
 * Pope Sixtus IV (1471–1484)
 * Pope Sixtus V (1585–1590)

Others

 * Sixtus of Reims (d. c. 300), bishop of Reims
 * Sixtus of Esztergom (d. 1285/86), Hungarian clergyman
 * Sixtus of Siena (1520–1569), Jewish Roman Catholic theologian
 * Prince Sixtus of Bourbon-Parma (1886–1934)
 * Albert Sixtus (1892–1960), German children's writer
 * Edmund Sixtus Muskie (1914–1996), American statesmen, 58th United States Secretary of State 1980–81
 * Prince Sixtus Henry of Bourbon-Parma (born 1940)
 * Sixtus Lanner (1934–2022), Austrian politician
 * Sixtus Leung Chung-hang (born 1986), Hong Kong activist and politician