Sphingomyelin deacylase

Sphingomyelin deacylase (, SM deacylase, GcSM deacylase, glucosylceramide sphingomyelin deacylase, sphingomyelin glucosylceramide deacylase, SM glucosylceramide GCer deacylase, SM-GCer deacylase, SMGCer deacylase) is an enzyme with systematic name N-acyl-sphingosylphosphorylcholine amidohydrolase. This enzyme catalyses the following chemical reaction


 * (1) an N-acyl-sphingosylphosphorylcholine + H2O $$\rightleftharpoons$$ a fatty acid + sphingosylphosphorylcholine;
 * (2) a D-glucosyl-N-acylsphingosine + H2O $$\rightleftharpoons$$ a fatty acid + D-glucosyl-sphingosine

The enzyme is involved in the sphingolipid metabolism in the epidermis.