Table tennis at the 2020 Summer Paralympics – Women's individual – Class 10

The Women's individual table tennis – Class 10 tournament at the 2020 Summer Paralympics in Tokyo took place between 25 and 30 August 2021 at Tokyo Metropolitan Gymnasium. Classes 6–10 were for athletes with a physical impairment in their upper body, and who compete in a standing position. The lower the number, the greater the impact the impairment was on an athlete's ability to compete.

In the preliminary stage, athletes competed in 3 groups of three or four. Winners and runners-up of each group qualified for the knock-out stage. In this edition of the Games, no bronze medal match was held. Losers of each semifinal were automatically awarded a bronze medal.

Results
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