Talk:Anorectic

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Ephedrine-containing products still available
As of Jan 2005, Americans can still buy OTC products that contain ephedrine, including many popular decongestants. Maybe the FDA only baned ephedrine in weight loss products. — Preceding unsigned comment added by 68.72.123.135 (talk) 06:41, 7 January 2005 (UTC)
 * The wording is "dietary supplements" . I've changed the article to reflect this. Reading between the lines of the FDA ephedra FAQ, it seems almost like they knew it would continue to be sold in other forms but didn't wish to draw attention to the fact.... Rkundalini 02:13, 10 Jan 2005 (UTC)

Amphetamine in first world war
Was it really used? In this page: Amphetamine and also other pages, it says they didn't discovered the medical effects of amphetamine until the 20s-30s, which is after 1st world war ended. — Preceding unsigned comment added by 213.67.208.212 (talk) 00:38, 5 September 2006

What's the opposite of this?
I want to know personally (stimulate my appetite). Plus it would be a nice addition. ImpIn | (t - c) 08:11, 12 June 2008 (UTC)

orexigenic Agottler (talk) 14:07, 8 May 2018 (UTC)agottler

Redirect
Can someone please redirect these terms "anorexigenic" and "appetite suppressant" to this article? —Preceding unsigned comment added by 59.101.48.57 (talk) 17:08, 14 June 2008

Redirects have been at the following links for some time:. Please ask again if that is not what you needed. --Hroðulf (or Hrothulf) (Talk) 13:40, 16 June 2008 (UTC)
 * anorexigenic
 * appetite suppressant

Unrelated passage in the article
"On January 18, 2008, the Botanic Gardens Conservation International (representing botanic gardens in 120 countries) stated that '400 medicinal plants are at risk of extinction, from over-collection and deforestation, threatening the discovery of future cures for disease.'"

This sentence was added on 27 October 08. It is not connected to the topic and does not add to the article. I am therefore moving it here. If it is placed back in the article, then it needs to be further worked on so that it does actually relate to the topic of the article.

I believe the author sees any plant-based medicines as inherently connected to all undiscovered plant-based remedies. This is a fallacy. This article is (or should be) about what we know of Anorectics. It should not be about idle speculation. We do have reason to believe that deforestation will endanger medicines that are yet to be discovered, but we have no reason to speculate about which types of medicines are available there. This belongs in a discussion about medicine in general, but it does not belong here. I could choose to speculate about the dozens of types of Anorectics that may be developed in a lab, but it would not belong in this article either. Unless an expert is willing to speculate as to how many Anorectics are yet to be discovered in those forests, then this doesn't belong here any more than my layman's speculation about laboratory progress.

Note that a botanist from those parts of the world speculation about how many undiscovered varieties of Apocynaceae there are local to them would be a legitimate bridge between the topics (reference please). I'm not saying that the topics cannot be connected, only that they haven't been. Any connection will be tenuous at best, but it can be done.

While I believe this sentence does not belong, I will note that the author seems legitimately interested in the topic. I am not accusing him of vandalism, merely of giving the above sentence insufficient thought.

--Gd2shoe (talk) 19:44, 31 March 2009 (UTC)

Terminology
What is the technical difference between an appetite depressant and an appetite suppressant, referenced in this article? Can we explain it a bit better?

FT2 (Talk 04:19, 24 May 2010 (UTC)

Is water an anorectic?
A recently publicised randomised controlled trial suggests that drinking water may act to suppress appetite. If this is true, would it count as an anorectic? So far, I've added the information I've found about this study to Appetite, but I wonder if it falls within the scope of this article.--greenrd (talk) 15:52, 25 August 2010 (UTC)

Yeah, it would, by definition, as would food. This article seems written by and for people who professionally deal with "-amines" and "-azines" and "-azones". As defined, drugs and anything that supplements diet which suppresses appetite is an anorectic. I'm guessing there are "alternative medicine" drugs that aren't listed, because there are Actual Medicine drugs that aren't listed, like nicotine especially paired with caffeine- ajcn.nutrition.org/content/77/6/1442.full and condensed at www.ncbi.nlm.nih.gov/pubmed/15955118 Since the most well-known and casually-observed anorectic nicotine isn't listed, I'm guessing this is a very incomplete list of mostly amphetamine-family chemicals.68.149.26.160 (talk) 03:44, 29 October 2013 (UTC)

Oxymetazoline
There's nothing in the source (that I can find) associated with the listing of Oxymetazoline (Afrin) that indicates it is an anoretic. Furthermore, I can't find anything to that effect on any page about Oxymetazoline anywhere. It seems to be completely unfounded, I'm suggesting it be removed (though I will leave the decision to someone more informed). 108.193.106.181 (talk) 23:33, 21 May 2012 (UTC)

There's a vague corroboration on this page (under "Adverse effects"), and other sources appear to suggest similarly that it can lead to anorexia as a side-effect, however I'm having difficulty finding primary sources. Since it is listed as anorectic in some secondary sources, perhaps we should leave it stet until there's definite information one way or the other. Jonsg (talk) 20:41, 5 September 2012 (UTC)

Hydralazine
seems to have possible anorectic effects. Worth adding it to "others"? thanks. Ben-Natan (talk) 16:01, 13 January 2015 (UTC)

Should we add Nicotine to the Anorectics list?
Ben, Ben-Yeudith (talk) 16:53, 4 September 2015 (UTC)

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Possible Additions
Adding nicotine to the list of anorectics

Current: Public health concerns Epidemics of fatal pulmonary hypertension and heart valvedamage associated with pharmaceutical anorectic agents have led to the withdrawal of products from the market. This was the case with aminorex in the 1960s, and again in the 1990s with fenfluramine (see: Fen-phen). Likewise, association of the related appetite suppressant phenylpropanolamine with hemorrhagic stroke led the Food and Drug Administration(FDA) to request its withdrawal from the market in the United States in 2000, and similar concerns regarding ephedrineresulted in an FDA ban on its inclusion in dietary supplements in 2004. A Federal judge later overturned this ban in 2005 during a challenge by supplement maker Nutraceuticals. It is also debatable as to whether the ephedrine ban had more to do with its use as a precursor in methamphetamine manufacture rather than health concerns with the ingredient as such.

[Added paragraphs]:

Nicotine has been the subject of public health concern because it is the primary addictive ingredient in tobacco products, which are the leading cause of preventable death worldwide. [2] While past legislation has proven to only reduce nicotine use by about 1% a year at best, the United States Family Smoking Prevention and Tobacco Control Act (FSPTCA) has given regulatory power to the FDA to reduce nicotine content in tobacco products.[3] Research has been conducted to determine the nicotine reinforcement threshold, a concept designed to specify what level of nicotine content should be allowed by the FDA.[4] Though nicotine content related addiction contributes to the health epidemic, the utilization of nicotine as an appetite suppressant and reluctance to cease use because of this is also a factor. About one-third of college students report that they use nicotine as an appetite supressant. The subsequent weight gain following cessation caused by an increased caloric intake and decrease metabolic rate in commonly reported as a reason for relapse. [1]

Because of the appetite suppressing properties, stimulant use is common associated with malnutrition. Counselors have began to focus on the symptoms of unhealthy stimulant use beyond behavior issues by investigating the physical symptoms that come with stimulant associated malnutrition. Particular drugs of interest are cocaine, amphetamine, and MDMA. Cocaine and amphetamines were reported to be associated with the most significant vitamin deficiencies. Reports conclude that cocaine is commonly associated with depletions of the vitamin B complex and vitamin C. Vitamin B deficiencies can cause decreasing in total motor function, with prominent symptoms of muscle tension, spasms, anemia, cold extremities, poor coordinations, and decrease in energy associated with ATP production. Vitamin C deficiencies can cause decreased immune function, sore gums, tooth decay, poor wound healing, and dry mouth and eyes. Amphetamines are commonly linked to anemia and blood clots. [4]

1. "Get it! Cornell". doi:10.1037/0022-006x.61.5.768&title=journal+of+consulting+and+clinical+psychology&volume=61&issue=5&date=1993&spage=768&issn=0022-006x.

2. Centers for Disease Control and Prevention (CDC) (2008-11-14). "Smoking-attributable mortality, years of potential life lost, and productivity losses--United States, 2000-2004". MMWR. Morbidity and mortality weekly report. 57 (45): 1226–1228. ISSN 1545-861X. .

3. Lundeen, Ronald E. (September 2009). "Tobacco under the FDA: a summary of the Family Smoking Prevention and Tobacco Control Act". Health Care Law Monthly. 2009 (9): 2–9. ISSN 1526-0704. .

4. Sofuoglu, Mehmet; LeSage, Mark G. (2012-09-01). "The Reinforcement Threshold for Nicotine as a Target for Tobacco Control". Drug and alcohol dependence. 125 (1-2): 1–7. doi:10.1016/j.drugalcdep.2012.04.023. ISSN 0376-8716. PMC 3419325 Freely accessible. .

Agottler (talk) 03:08, 8 May 2018 (UTC)agottler