Talk:Arsphenamine

was
was this drug successful in treating syphilis? Kingturtle 00:11, 24 Dec 2004 (UTC)


 * See [] -- TN 5th July 2005
 * This link, 1, does not work; please correct. Autodidact1 (talk) 22:52, 28 July 2020 (UTC)

copyright violation?
The text is almost if not identical to that @ http://salvarsan.biography.ms/.

Courtland 16:50, 2005 Mar 26 (UTC)

Revised and corrected based on published literature.

Courtland 17:59, 2005 Mar 26 (UTC)

--Zeamays 17:52, 9 June 2006 (UTC)
 * Someone who understands Wiki reference formatting needs to revise the reference formats, which are a jumble of formats.

structural formula
I would like to mention that already Cullen and Reimer in their comprehensive review on Arsenic Speciation in the environment (Chem. Rev. 1989, 89,713-764) mention that the structural formula of Salvarsan as represented with a double bound was incorrect and cite for this statement two articles from 1977 and 1979: Sarquis, M. ''J. Chem. Edu.'' 1979, 56, 815 Levinson, A. S. ''J. chem. Educ.'' 1977, 54, 98

therefore the statement that the true structure of this substance was only found in 2005 is not correct, at least not by itself, though of course it is possible that is was only in 2005 that this was proved.

Bereschit2007 15:01, 24 February 2007 (UTC)

shows the structure of salfarsan as 6 membered ring and this is printed way before 2005.--Stone 16:29, 4 September 2007 (UTC)

I would just like to note two things - the 2005 research was not crystallographic as stated in the box with the chemical formula. And that the structure of "Salvarsan" appearing on that banknote appears to be the phenyl equivalent of Salvarsan - which was solved by crystallography by the Russians (i can get refs for this if interested..) It was long thought that the As=As structure was impossible but the final proof that Salvarsan was cyclic compounds was the 2005 paper. The prior literature to suggest that Salvarsan was not As=As seems to be very vague in how it came to that conclusion. —Preceding unsigned comment added by 203.109.163.127 (talk) 01:59, 20 November 2008 (UTC)

The above is correct, it is hard to ascertain where the cyclic structure featured on the German banknote pictured came from as there was little published before the Angew. Chem. paper which proved that the cyclic structure was correct. The assumption is made that the structure on the bank note was borrowed from the studies on the Phenyl compound, which was prepared in the same way. People had guessed at this because the As=As structure was improbable but no real evidence had been collected before the ESMS studies which were published in the Angew. Chem. 2005 paper. —Preceding unsigned comment added by 122.59.76.204 (talk) 14:56, 7 May 2011 (UTC)

who discovered salvarsan?
the article states Jordan Wilson discovered Salvarsan yet Mentions Hata at the end of the paragraph. Doraemonsan (talk) 14:40, 18 May 2009 (UTC)

Salvarsan was first prepared (discovered) in Paul Ehrlich's lab, most likely by A. Bertheim. Hata was the one who first tested the drug in animal models under Ehrlich's direction. —Preceding unsigned comment added by 122.59.76.204 (talk) 14:59, 7 May 2011 (UTC)

Very low utility
These sites: [Book 1] and [Book 2] have books writen in 1910 decade, about arsphenamine.

In fact, arsphenamine was toxic painfull and almost useless. To example, Lenin used this drug and even so, he died of syphillis in 1924.Agre22 (talk) 23:14, 11 January 2010 (UTC)agre22
 * I liked your comments about arsphenamine, but you don't provide a link to any sources for your statement that Lenin died of syphilis (not "syphillis [sic]". Please expand. Autodidact1 (talk) 22:57, 28 July 2020 (UTC)

Chemical Instability due to Ignorance ?
"This instability may be due to the fact that the true structure of the compound was not confirmed until 2004." Doesn't seem right somehow... g4oep

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Salvarsan featured in Kurosawa's The Quiet Duel (1949)
This drug and its use is a centerpiece of this post-war film. Rmsquires (talk) 03:25, 10 July 2023 (UTC)