Talk:Aspirin-exacerbated respiratory disease

Paracetamol is not an NSAID, as may be understood from the wording "though paracetamol is generally considered safe" — Preceding unsigned comment added by 88.90.68.85 (talk) 15:32, 21 September 2011 (UTC)

The pathogenesis section is extremely confusing. In particular, the way the sentence describing differential PGE modulation I found difficult to understand. — Preceding unsigned comment added by 99.98.209.88 (talk) 14:09, 22 January 2013 (UTC)

Has anybody else encountered this condition with the additional symptom of severe acute pain around diaphragm & back (possibly associated with gallbladder/spleen) and, later, likely autoimmune haemolytic anaemia? — Preceding unsigned comment added by 95.151.241.169 (talk) 19:52, 25 September 2013 (UTC)

Also, interested in finding out more about the efficacy of aspirin desensitization for this condition. Does it reduce sensitivity to other allergens, such as ibuprofen & certain tree pollens (salicylate perhaps)? Does it really prevent or delay nasal polyps returning? Any dangers (when supervised by a GP)? — Preceding unsigned comment added by 95.151.241.169 (talk) 20:13, 25 September 2013 (UTC)

Allergy or intolerance
Is this an allergic reaction or an intolerance? Jim Derby (talk) 13:37, 5 March 2014 (UTC)

Neither, exactly. It is not considered an autoimmune disorder, but it is considered a chronic immune dysregulation. Andyleigh12 (talk) 14:29, 31 July 2018 (UTC)

Page Title
Is there a reason that the title of this page is Aspirin Induced Asthma as opposed to AERD (Aspirin Exacerbated Respiratory Disease) or NERD (NSAID Exacerbated Respiratory Disease)? For clarification, AERD and NERD refer to the same disorder - NERD is not used in English speaking countries due to the unfortunate acronym. Either way, "Aspirin Induced Asthma" is an outdated name for this disorder. It is referred to as AERD or NERD in all modern research. "Aspirin Induced Asthma" was moved away from because it does not adequately describe the disease, which involves more than asthma and involves all NSAIDs - not only aspirin. I would propose that the name of this page be changed to Aspirin Exacerbated Respiratory Disease since that is the most widely used name and the name used in the vast majority of modern research. Andyleigh12 (talk) 14:41, 31 July 2018 (UTC)

Incorrect Reference
"NSAIDs that are highly selective in blocking COX-2 and do not block its closely related paralog, COX-1, such as the COX-2 inhibitors celecoxib and rofecoxib, also are regarded as safe.[10]" The reference quoted to support this does not mention aspirin at all.

10.

TiredOfLondon (talk) 13:44, 24 November 2018 (UTC)