Talk:Cefuroxime

My mother was healed tuberculosis for 5 years. Suddenly there is enlarge nodes at her back neck. She was asked to take a biopsy with the ENT clinic. In the same time, the doctor recomand her to take cefuroxime. But for 2 times taking the medcine, makes she looks fatter. Does the cefuroxine makes the cause?

IUPAC Name needs stereochemistry
IUPAC Name should be:

(6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2E)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid--ChemSpiderMan (talk) 03:41, 26 May 2008 (UTC)
 * No, this is a (Z)-compound (source: Merck Index 14th Edition, p. 323). Best regards, --Jü (talk) 18:39, 5 June 2011 (UTC)

Structural formulae in the box
Structural formulae shows a (E)-C=N-double bond. This is wrong. According to Merck Index 14th Edition, p. 323 Cefuroxime has a (Z)-C=N-double bond. Best regards, --Jü (talk) 18:39, 5 June 2011 (UTC)


 * I wouldn't use the Merck Index as your only source of structural information, especially conformation. Nonetheless, I think you are correct. I've looked at the crystal structures of various similar cephalosporins, and of protein-bound cefuroxime (PDB 1QMF), and the oxime methoxy is always trans to the heterocycle (furan or thiazole). See, for example, ceftizoxime in A. Miyamae, S. Koda, Y. Morimoto, Chem. Pharm. Bull. (1986) 34 3539–3548 (CSD code FAJMAE). I have updated the image accordingly. --Ben (talk) 11:59, 9 June 2011 (UTC)

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Cefuroxime
Is it safe to take alcohol after taking cefuroxime Roy Shapure (talk) 06:59, 23 April 2018 (UTC)