Talk:Chelation therapy

Is chelation commonly used for horses or other animals? Any research on animals?
If we find out for example that chelation of cadmium prevents many cases of prostate in laboratory animals, then it might work for humans also.

128.214.78.210 (talk) 17:37, 24 July 2016 (UTC)

Virtually all drugs are tested on animals as part of the clinical trials process, at least in the EU and the USA. It would be very difficult, if not impossible, to place a drug on the market that *hasn't* been tested on animals. Note that it is only one stage (not the first, or last) of the process - meany drugs that are effective on surrogate animals are not effective in humans.

NB: before anyone gets in a huff about animals testing, clinical trials must pass an ethics board and animal testing is only approved where necessary for human health. It is very difficult these days, for example, to get approval for animal testing for perfumes or cosmetic compounds. 212.194.114.50 (talk) 13:42, 27 June 2017 (UTC)
 * wp:notforum

not MEDRS
Under "Society and culture - Use in alternative medicine - Cardiovascular disease" 4th paragraph

"In 1988, a retrospective study of 2870 patients treated with EDTA chelation found that 77% of patients with ischemic heart disease showed "marked" improvement and 91% of patients with peripheral heart disease also showed "marked" improvement.[19] A 1993 retrospective study of 470 patients who underwent EDTA chelation noted that 80% had objective evidence of improvements of their symptoms.[40]"

I would be highly surprised if "Medical Hypotheses" and "Journal of Advancement in Medicine" adhere to MEDRS and should be removed. 2A02:A210:A001:A380:6435:5369:3F04:B220 (talk) 21:01, 9 September 2017 (UTC)
 * Thanks for pointing that out. remove it and some other primary/unreliable sources. Jytdog (talk) 21:05, 9 September 2017 (UTC)

What is MEDRS ? I have tried to look it up, and expected that to be easy, as the un-named commentator who used it wrote as if it referred to a common research protocol. I note that the reference numbers, 19 and 40, provided in the comment are not functional, here or on the article page, so I have no convenient way to look up these reports. Janice Vian, Ph.D. (talk) 22:52, 14 September 2017 (UTC)


 * See WP:MEDRS. The journal Medical Hypotheses is especially suspect, having a (ahem) unconventional approach to peer-review and having published crap from anti-vaxxers and AIDS denialists. Famous  dog   (c) 07:55, 15 September 2017 (UTC)


 * This is further non-MEDRS content and sources, so is removed to here for discussion, if warranted. The edit contains trademarks, dubious content in low-quality sources, and promotional, misleading quackery. Zefr (talk) 22:20, 10 October 2020 (UTC)

Chelation for Autism
There is actually evidence that chelation can help for people with authism: Conclusion: Overall, both one and seven rounds of DMSA therapy seems to be reasonably safe in children with ASD who have high urinary excretion of toxic metals, and possibly helpful in reducing some of the symptoms of autism in those children. https://pubmed.ncbi.nlm.nih.gov/19852790/ 31.165.215.228 (talk) 18:51, 20 January 2023 (UTC)

Iron and Chronic Heart failure - Iron chelation to the rescue
Iron induces chronic heart failure in half of heart attack survivors, according to landmark study

"....iron chelators reduce iron content within the heart tissue."

https://www.mbi.ucla.edu/in-the-spotlight

Sometime in the near future, the section on Iron and Heart may have to be revised and updated. 104.35.48.79 (talk) 05:52, 30 January 2023 (UTC)

Alternative? Really?
I find it... disturbing to see, "This article is part of a series on Alternative medicine" displayed so prominently on the page. Chelation therapy is an effective, main-stream treatment for several different kinds of metal poisoning. Whether or not autism and heart disease and cancer are caused by low-level metal poisoning that goes unrecognized by main-stream medicine, and whether or not those conditions can be reversed by chelation therapy is a different question.

If a meme catches fire on the internet saying that Penicillin cures warts, will we then label Penicillin as "alternative medicine?" 151.201.129.79 (talk) 23:33, 2 January 2024 (UTC)
 * I have removed the sidebar as it gives too much weight to the alternative use. (That will likely be reverted.) This article, unfortunately, deals with both mainstream and alternative/quack uses. We normally have separate articles for alternative medical articles. Not sure what happened here. -- Valjean (talk) ( PING me ) 02:14, 3 January 2024 (UTC)
 * Agree. -- Dustfreeworld (talk) 17:57, 29 May 2024 (UTC)

Dustfreeworld, I see you left an edit summary at Template:Alternative medicine sidebar when you deleted Chelation therapy from the sidebar:
 * "Changed my mind and self-revert. Sorry I was wrong. It’s not alternative https://pubmed.ncbi.nlm.nih.gov/?linkname=pubmed_pubmed&from_uid=27199065"

Please explain what you mean. -- Valjean (talk) ( PING me ) 20:46, 29 May 2024 (UTC)