Talk:Clostridium perfringens

Nagler's reaction.
Cl. Perfringens is grown on medium containing 6% of agar, 5% of fildes peptic digest of sheep blood and 20% human serum or 5% egg yolk in a plate. To one half of the plate, antitoxin is spread on the surface. The inoculated culture plate is incubated at 37°c for 24 hours. Colonies on the half plate without the antitoxin will be surrounded by opacity while colonies on other half with antitoxin show's no opacity due to the specific Neutralisation of the alfa toxin. Alpha toxin splits lecithin into phosphoryl choline and a diglyceride(lipid). The lipid deposits around the colonies resulting in opacity.

Gas gangrene from food poisoning???
I removed "Some strains of C. perfringens produce toxins which cause gas gangrene if ingested." Surely this can't be right???? --213.31.11.107 (talk) 10:57, 23 April 2009 (UTC)

Use in Salt Rising Bread
According to http://home.comcast.net/~petsonk/index_files/Page416.htm, this organism can be used instead of yeast to make bread rise. If true, that use is worthy of mentioning. Another reference: http://www.ncbi.nlm.nih.gov/pubmed/18646681/ Kevink707 (talk) 19:38, 19 July 2010 (UTC)

Content and Citation
Citations should be added to 1st section paragraphs 2,3, Food Poisoning paragraph 2 and 3, Infection paragraph 1 and the sections diagnosis and treatment.

Also the paragraph about mobility has several sentences that seem to be to similar to the original article's wording (if not an exact copy). Paraphrasing as "C. perfringens has filaments surrounding its entire body allowing it to move. This structure allow them to move quickly from the original colony, causing them to appear at the edges of the agar. As a result the motility is similar to that of bacteria with flagella " would help fix this problem.

I also think it would be great benefit to this article to add information about the microbes metabolic processes. That it uses enzymes to facilitate glycolysis, and to survive the bacteria uses toxins and enzymes to break down host tissue into amino acids that it cannot create on its own. By adding this I think it will connect the microbes processes with the reaction to human or other host's living tissue (necrosis).

Michaellar (talk) 00:21, 20 September 2016 (UTC)

Removed/Rewrote sections that were copied and pasted from other sources
"Very rare, fatal cases of clostridial necrotizing enteritis (also known as pigbel) have been known to involve "Type C" strains of the organism, which produce a potently ulcerative β-toxin." Was copied from Microbes: Concepts and Applications By Prakash S. Bisen, Mousumi Debnath, G. B. Prasad, therefore I have supplied a paraphrased version of the same information. and cited the source.

Michaellar (talk) 01:56, 27 September 2016 (UTC)

"Outbreaks can cause regularly..."?
I'm not sure what was intended here.

Wiki Education assignment: MIBO 3500 Introduction to Microbiology
— Assignment last updated by Cowboy122 (talk) 13:49, 5 October 2023 (UTC)

Tissue gas
In human post-mortem bodies C. perfringens can cause extremely accelerated decomposition. The by-product, called tissue gas, is slowed or halted by embalming the body using special additive chemicals. It most commonly occurs in the bodies of people who have died of gangrene, large decubitus ulcers, necrotising fasciitis or who have had soil, faeces or water forced into wounds.

This section was copied and pasted from the provided source. Oblivious2 (talk) 17:52, 1 October 2023 (UTC)