Talk:Heterocyclic amine formation in meat/Archive 1

Carol - Wow! I learned a lot! (glad I am a medium-raw type of person...) Sorry I came here much later than others (didn't see the 'discussion' tab until this morning. shame on me.). I marked a few areas on your page, bolded. I probably would have 'talked' here first if I had known this earlier... Virginia 507WVS (talk) 11:13, 22 November 2011 (UTC)

Very informative topic. It seems like you have covered all the bases, but I found a paper while browsing that may provide some additional information about studies that might allow you to establish some causality (http://www.aapn.org/hca1.html). Good work! -Joe 570jby (talk) —Preceding undated comment added 18:44, 9 December 2011 (UTC).

Really interesting topic, 24 times more carcinogenic than aflatoxin!?! A suggestion (and I aplogize I'm trying to figure out how to mention this correctly) is that it would be nice to see that statement qualified by dose. IE - how does the dose of carcinogen from heterocyclic amines from a large well-done steak relate to a pack of cigarettes. Hope that makes sense.....Nice work. Just realized I wrote this before I knew how to sign it.....(570wac (talk) 22:52, 10 November 2011 (UTC))

Carol, I was looking at your references and noticed you had the same reference listed multiple times. There is a way to condense the list so that they are only listed once. You can take a look at my page for help on this or, if you want I can clean it up once you are done filling out the sections. -Vic 570vca (talk) 20:16, 3 November 2011 (UTC)

Alright, think I got rid of the duplicate references. Let me know if I missed one. -Vic 570vca (talk) 17:30, 6 November 2011 (UTC)

Carol, wonderful job. I found this information on breast cancer and HCAs. Studies show meat intake to be a breast cancer risk factor, even when confounding factors, such as total caloric intake and total fat intake, are controlled. Part of the reason may be that meat becomes a source of carcinogens and/or mutagens, such as HCAs, that are formed while cooking meat at high temperatures. A review of HCAs showed that certain HCAs are distributed to the mammary gland and that humans can activate HCAs metabolically. As a consequence, frequent meat consumption may be a risk factor for breast cancer. I am glad that I am not a big meat eater. 570nlh (talk) 18:20, 7 November 2011 (UTC)Nancy Hannaway

Ah, does this mean that I can't have grill marks on my burgers anymore? The confounding in this study must be enormous. A diet high in meat is probably enough to kill you, regardless of how you cook it. I thought you addressed that well in the concluding paragraph. Are there any studies out there that show that alternative cooking methods are much better? Ceci 570csc (talk) 03:29, 12 November 2011 (UTC)

May i know whether Table 2. is the same as Content of four HCAs in ground beef cooked under normal home conditions? if so, i think it will be more clear if cooked under normal conditions is added. BTW, since i m an Asian, i am wondering whether the normal home conditions are the same for Americans and Asians? (570lil (talk) 15:23, 15 November 2011 (UTC))

I took a look at the "heterocyclic amine" wiki page and it definitely needs some updating. Were you planning on incorporating your information into that page or creating a whole new page? I did my wiki page on PhIP (and have very similar information). I would not have needed to include so much if the now standing HCA page were updated w/ your info. Your page is great and very informative. I really liked the meat consumption data and pic! Christi 570ces

Excellent article Carol. For your consideration, I added a short statement in the epidemiological studies section mentioning there are currently no federal guidelines associated with consumption of HCA levels in meat. The reference is from 2010 so hopefully it is not too outdated. Please feel free to use, modify, or delete the change as you see fit. Dan (570ddt (talk) 01:42, 17 November 2011 (UTC))

Ugh. Glad we decided to have leftovers instead of burgers tonight. I am tempted to find a photo of a nice juicy burger to add, but maybe that is too much. Nice article. 570ceh (talk) 01:35, 21 November 2011 (UTC) Claire