Talk:MDMA

Is MDMA a psychedelic or not?
The best source for this claim is that there may be 5HT2A agonism, which "supposedly contributes" to "mild psychedelic hallucinations" caused by "high doses" of MDMA. That's a lot of words to say that its status as a psychedelic is pretty flimsy.

The other sources don't support that it is one, either, just that it's commonly referred to as one. This is similar to how cocaine is called a "narcotic," a legal stipulative definition that's quite different from the scientific one.

I'm not arguing that MDMA isn't a psychedelic, but if these are the best sources we have I think it should be removed from the lead. 2600:1017:B103:D814:CCC9:7381:FFDB:5A2D (talk) 17:51, 13 December 2023 (UTC)


 * MDMA is not in any way, shape or form, a classic psychedelic, meaning that it cannot be directly compared to LSD, psilocybin, or even mescaline, but it is somewhat closer to mescaline than many other things that people consider to have psychedelic properties, such as cannabis, ketamine, salvia divinorum, and even muscimol. The lead says it has "minor psychedelic properties", but that doesn't mean that it is a psychedelic. Perhaps we just need some clarification in the lead that while it has minor psychedelic properties, it is not technically a psychedelic. Thoric (talk) 18:35, 13 December 2023 (UTC)

Bruxism → Chewing Gum?
Should we add that some users chew gum in order to deal with grinding teeth? Since the article is semi-protected, I wanted to check before just adding it in (especially since finding a good source for this is trickier than I though). Niplav (talk) 13:57, 7 February 2024 (UTC)

The role of Danny Leclère in the production of XTC as partydrug
I have a proposition to add some text regarding Danny Leclère who developed in the 1990's a formula to produce "pure XTC" as party drug and set up a worldwide illegal network to have the drugs distributed. It's because if him XTC became popular in nightlife. The formula of Leclère is still the most used in the manufacturing of (illegal) XTC. Valid/Trusted references can be found in the article about Danny Leclère. I think a short topic in the article of MDMA is advisable due to Leclère his role in production/distribution of illegal XTC. Ino mart (talk) 15:31, 6 March 2024 (UTC)


 * is "pure XTC" MDMA? Bon courage (talk) 15:55, 6 March 2024 (UTC)
 * According the documentary "Bad, Bad Belgium" the term "pure XTC" refers to the formula by Leclère: it is the first XTC-formula which only contains MDMA as drug. At that time, MDMA-drugs also contained other ingredients such as meta-Chlorophenylpiperazine and para-Methoxy-N-methylamphetamine.

Section on medical use outdated, US-centric, and wrong
The section incorrectly reads "As of 2017, MDMA has no accepted medical indications.[where?] Before it was widely banned, it saw limited use in psychotherapy. In 2017 the United States Food and Drug Administration (FDA) approved limited research on MDMA-assisted psychotherapy for post-traumatic stress disorder (PTSD), with some preliminary evidence that MDMA may facilitate psychotherapy efficacy for PTSD.".

MDMA has been approved for the treatment of PTSD in Australia (https://www.tga.gov.au/news/media-releases/change-classification-psilocybin-and-mdma-enable-prescribing-authorised-psychiatrists). The accepted medical indication in this case is thus PTSD.

Additionally, the paragraph is very US-centric, in a way that does not fit Wikipedia.

Suggestion to edit the paragraph to: "In 2023, MDMA was approved for the treatment of PTSD in Australia. As of June 2024, it is currently not approved for medical use in other countries." 158.174.187.29 (talk) 12:58, 8 June 2024 (UTC)

Semi-protected edit request on 18 July 2024
Add a “metabolism” section going more in depth about the bodies metabolism of the drug, like how it is metabolised by CYP2D6 into MDA through demethylation Big Mocc (talk) 22:09, 18 July 2024 (UTC)
 * Red information icon with gradient background.svg Not done: please provide reliable sources that support the change you want to be made. Left guide (talk) 23:47, 18 July 2024 (UTC)