Talk:Paraventricular nucleus of hypothalamus

Untitled
The article says paraventricular nucleus (PVN) ... is not to be confused with the periventricular nucleus (PV). However, the caption of the image is: Paraventricular nucleus is 'PV', at center top, in blue. 06:36, 12 March 2007 Snowbot/Snowolf
 * Replaced figure with newly created one for human with proper label. Sammyj 13:36, 12 March 2007 (UTC)

This article contains what appears to be fairly accurate and useful information; however, it contains no references to any studies which back up any of the information. Can anyone provide references? Basic research is preferable to review articles, in my opinion, because I have found that review articles fairly regularly cite sources that do not actually support the specific claim made in the review. My current project involves the PVN, so I may be able to provide a few in the future, but I highly doubt that my set of knowledge is exhaustive.

128.143.43.144 (talk) 21:05, 17 January 2008 (UTC)

It should also be noted in the article that there is a paraventricular nucleus of the thalamus, which is significantly different in location and function, but deceptive for those who are unaware. The paraventricular nucleus of the hyptothalamus (this article) is generally abbreviated as "PVN", while the paraventricular nucleus of the thalamus is generally abbreviated "PVT".

128.143.43.144 (talk) 21:08, 17 January 2008 (UTC)

"Neurons" section
The opening paragraph of this section now reads:

"The PVN contains magnocellular neurosecretory cells whose axons extend into the posterior pituitary, parvocellular neurosecretory cells that project to the median eminence, and several populations of peptide-containing cells that project to many different brain regions."

Because the explanatory wording associated each of these three types is irregular, the reader may be led to suspect that it implies differences among them, which I doubt is intentional. For example, the axons of the first type "extend." The second type "project," and there is no mention of axons. The third type are apparently very diverse, and are distinguished by the presence of peptides within them.

The discussions of these types appearing immediately below this introductory paragraph are strangely at odds with it. The third type, apparently, has nothing to do with peptides, but rather is notable for the connections they make, which are "central," or "going to the brain."

(Rather than attempting to correct these peculiarities and to risk getting it wrong, I've decided to draw attention to them.) Unfree (talk) 17:07, 10 June 2008 (UTC)

"Location" section
The last paragraph reads:

"The PVN is highly vascularised and is protected by the blood-brain barrier, although its neuroendocrine neurons extend to sites (in the median eminence and in the posterior pituitary) beyond the blood-brain barrier."

The problem is with understanding which neurons are the "neuroendocrine" ones. They aren't mentioned in the following discussion (of the types of neurons in the PVN), and the word "neuroendocrine" is linked to an article on neuroendocrinology -- a most unhelpful link! Unfree (talk) 18:00, 10 June 2008 (UTC)