Talk:Pemphigus

Talcum Powder Citation
Here's one... it says citation needed... I just don't know how to add it:

http://www.mayoclinic.com/health/pemphigus/DS00749/DSECTION=9

MiniMary12 21:08, 4 December 2007 (UTC)

Headline text
omg! what is that disease that makes people look like birds and they die really early in life? if you know please e-mail at aj4dolphin@yahoo.com

Pemphigus
I had a grandmother who was diagnosed with pemphigus when she was 62 years old. She passed away in 2001 at the age of 91. She had to live with this virtually unknown disease for a long time. Her first symptoms had to do with her eyes. Her lids were turning inward because of the drying out of her eyes. Needless to say she began undergoing different surgical procedures that just didn't work. She eventually became blind. This also affected her nose and throat. She had so much scar tissue built up in her throat that she could only eat pureed, watered-down baby food and drink nutrition drinks. She was miserable until the day she died.

My question is this: Can this be hereditary. I am in my mid fifties. I have constant eczema on my scalp, have a recurring mouth infection that just doesn't seem to go away. There are places on my fingers by my nails that seem to crack, split and peel no matter the amount of lotion or medicine I put on them. Should I look into the possibility of this? Would there be another avenue for me to pursue?

Thank you,

74.84.0.69 16:22, 2 October 2007 (UTC)Deborah Lawson jesstjmom@bwoodtx.com

glue and keeps the cell together
this phrasing should be improved to say what is exactly going on here... desmosomes, basement membrane zone problem, hemidesmosome, etc... overall, I think this could be made more technical.

Wonderful reference article to add

 * First, there is a wonderful Dermatologic therapy article that I referenced in this entry, and I think if someone has more time, more content could be cited from it. The article is: Yeh, S.W; Ahmed, Babar; Sami, Naveed; Ahmed, A. Razzaque. "Blistering disorderes: diagnosis and treatment." Dermatologic therapy. 2003;16(3):214-23. .  I can email it to you if you contact me.


 * Second, if you are interested in the skin, adnexa, or dermatology, I would love some help over at WP:DERM... just fyi. kilbad (talk) 05:19, 11 November 2008 (UTC)

Another great reference to add
-- I just ran across this in the course of other work and don't have time to add a reference, but something along the lines of "A small study in 2012 reported that rituximab, a drug used to treat other auto-immune diseases, such as rheumatoid arthritis, appears to be effective in treating pemphigus. The researchers call for further research on this possibility." -- Here's the reference: Arch Dermatol. 2012 Feb 20. [Epub ahead of print], "Effect of a Single-Cycle Alternative Dosing Regimen for Rituximab for Recalcitrant Pemphigus: A Case Series of 9 Patients." Matsukura S, Knowles SR, Walsh S, Shear NH.PMID: 22351790 Sorry to leave this for someone else! Celia Kozlowski (talk) 20:36, 29 February 2012 (UTC)

Cleaned up external links section
This section should be used to send people to general resources, not specific articles on aspects or treatments, unless they are overview review articles.

Lancet
Seminar 10.1016/S0140-6736(19)31778-7 JFW &#124; T@lk  14:41, 6 September 2019 (UTC)