Talk:Polycythemia vera

Prognosis
What is the prognosis? Linuxo (talk) 17:54, 2 June 2018 (UTC)

I
I have PV. The following part may need review: The tendency to avoid chemotherapy if possible, especially in young patients, is due to research indicating increased risk of transformation to AML, and while hydroxyurea is considered safer in this aspect, there is still some debate about its long-term safety.

I am pretty sure I remember that my oncologist told me that the studies linking hydroxyurea to AML are suspect, and that newer studies indicate it might even reduce the incidence of progression to AML.


 * We need a reliable source that says this. Can you find one?  WhatamIdoing (talk) 05:35, 13 April 2008 (UTC)


 * Too late. My oncologist retired.  I'll ask the new one if I remember to.  But I note there is no reliable source cited for the bit I objected to.  "Increased risk of transformation to AML" ought not to be tossed off lightly.  People could balk at the treatment they need. Jive Dadson (talk) 06:31, 10 August 2009 (UTC)

Hydroxyurea
My doctor prescribed hydroxyurea to bring down my platelet count. The article says only that it is prescribed to bring down the hemocrit. Phelbotomies alone kept my hemocrit within bounds, but not platelets. Jive Dadson (talk) 22:06, 16 December 2008 (UTC)

Polycythemia rubra vera
Why does that forward to the article for polycythemia instead of this article? 24.99.86.24 (talk) 19:23, 10 January 2009 (UTC)

Phlebotomy and hydroxyurea
I did a little editing about when hydroxyurea is indicated. I have PV, and I take hydroxyurea daily. It was not indicated (for me) due to too many blood-lettings being necessary. The oncologist (now retired) said that blood-letting alone does not control excessive platelet production. Around here, (California USA), the normal regimen is daily maintenance with hydroxyurea with phlebotomies only when indicated by blood tests.

I do not have all the references and citations I would need to add that information, so I only removed the assertions that I know to be incorrect because of my personal counter-example and others I see at the clinic. Again, I urge people to edit this Wiki page like walking on eggs. Being diagnosed with an incurable blood disease can put a person into a panic. Be careful.

I see someone changed all the occurrences of "phlebotomy" with "venesection." I was not familiar with the word "venesection." (Neither is my spell-checker.) In these parts, (California USA), it is always called "phlebotomy." From the roots, both words literally mean "vein-cutting." I put in one reference to "phlebotomy." Jive Dadson (talk) 01:58, 18 December 2010 (UTC)

External links modified
Hello fellow Wikipedians,

I have just added archive links to 1 one external link on Polycythemia vera. Please take a moment to review my edit. If necessary, add after the link to keep me from modifying it. Alternatively, you can add to keep me off the page altogether. I made the following changes:
 * Added archive https://web.archive.org/20080902020159/http://news.yahoo.com:80/s/ap/20080826/ap_on_sc/toxic_dump_fears to http://news.yahoo.com/s/ap/20080826/ap_on_sc/toxic_dump_fears

When you have finished reviewing my changes, please set the checked parameter below to true to let others know.

Cheers. —cyberbot II  Talk to my owner :Online 10:25, 19 October 2015 (UTC)

Review
10.1111/bjh.13812 JFW &#124; T@lk  09:25, 27 October 2015 (UTC)

Relation between ESR(Erythrocyte Sedimentation Rate) and Zeta potential(ζ, in mV)in Polycythemia: ζ decrease is due to higher RBC aggregation (Erythrocyte Aggregation, EA). ESR is directly linked to EA. Higher ESR, higher EA. On the other hand lower EA means higher ζ. So when ESR decreases is because EA decreases and consequently ζ increases. The opposite is written in the article. I believe that ζ increase is clear due to higher hematocrit (more particles, more electrical charge). — Preceding unsigned comment added by Antonio valadão (talk • contribs) 19:47, 7 May 2018 (UTC)