Tennis at the 1999 Pan American Games – Men's singles

Men's singles at the 1999 Pan American Games was won by Paul Goldstein of the United States.

Seeds

 * 1) 🇺🇸 Cecil Mamiit (finalist)
 * 2) 🇺🇸 Paul Goldstein (champion)
 * 3) 🇧🇷 André Sá (third round)
 * 4) 🇻🇪 Maurice Ruah (third round)
 * 5) 🇺🇸 Bob Bryan (quarterfinalist)
 * 6) 🇧🇷 Paulo Taicher (semifinalist)
 * 7)  Federico Dondo (quarterfinalist)
 * 8) 🇧🇷 Daniel Melo (quarterfinalist)
 * 9)  Hermes Gamonal (third round)
 * 10) 🇻🇪 Yohny Romero (third round)
 * 11) 🇨🇺 Lázaro Navarro-Batles (third round)
 * 12) 🇲🇽 Marco Osorio (third round)
 * 13) 🇲🇽 Óscar Ortíz (quarterfinalist)
 * 14) 🇦🇷 David Nalbandian (semifinalist)
 * 15) 🇦🇷 Edgardo Massa (third round)
 * 16)  Adrián García (third round)