Thomas and Lois Wheless House

Thomas and Lois Wheless House is a historic home located at Louisburg, Franklin County, North Carolina. It was built in 1954–1955, and is a one-story, rectangular Modern Movement style dwelling of glass, wood, and stone. It has a low-pitched gable roof, rests on a concrete-slab foundation, and measures 30 feet wide and 72 feet deep.

It was listed on the National Register of Historic Places in 2007.