Trey Sermon

An'treyon Sermon (born January 30, 1999) is an American football running back for the Indianapolis Colts of the National Football League (NFL). He played college football for the Oklahoma Sooners and Ohio State and was selected by the San Francisco 49ers in the third round of the 2021 NFL draft.

Early years
Sermon attended Sprayberry High School in Marietta, Georgia. He committed to the University of Oklahoma to play college football.

Oklahoma
As a true freshman at Oklahoma in 2017, Sermon played in all 14 games and made three starts. He finished the season with 744 yards on 121 carries with five touchdowns. As a sophomore in 2018, he shared time with Kennedy Brooks, rushing for 947 yards on 164 carries and 13 touchdowns. As a junior in 2019, he played in nine games and had 54 carries for 385 yards and four touchdowns.

Ohio State
Sermon transferred to Ohio State University as a graduate student in 2020. In the 2020 Big Ten Championship Game against Northwestern University, Sermon's 331 rushing yards were the most in a single game by an Ohio State player and the highest ever in a Football Bowl Subdivision championship game. In the 2021 Sugar Bowl versus Clemson, Sermon rushed for 193 yards and scored a rushing touchdown along with catching 4 passes for 61 yards in a 49–28 victory. In the 2021 National Championship Game against Alabama, Sermon got injured on the first play of the game and did not return.

San Francisco 49ers
Sermon was drafted by the San Francisco 49ers in the third round (88th overall) of the 2021 NFL draft. He signed his four-year rookie contract on July 21, 2021.

Sermon entered his rookie season in 2021 as the third-string running back behind Raheem Mostert and fellow rookie Elijah Mitchell. He made his first career start in Week 3, where he rushed for 31 yards and a touchdown with two catches for three yards and another touchdown against the Green Bay Packers. He suffered an ankle injury in Week 12 and was placed on injured reserve on December 4, 2021. He was activated on January 11, 2022. As a rookie, he appeared in nine games and started two. He totaled 41 carries for 167 rushing yards and one rushing touchdown.

Sermon was released by the 49ers on August 31, 2022.

Philadelphia Eagles
On September 1, 2022, Sermon was claimed off waivers by the Philadelphia Eagles. He appeared in two games, Weeks 4 and 5, in the 2022 season.

Sermon was waived/injured by the Eagles on August 29, 2023. He reverted back to injured reserve two days later. On September 15, 2023, the Eagles waived Sermon from injured reserve.

Indianapolis Colts
On September 19, 2023, Sermon was signed to the practice squad of the Indianapolis Colts. He was promoted to the active roster on September 23. He appeared in 14 games for the Colts in the 2023 season. He recorded 35 carries for 160 rushing yards.

On March 14, 2024, the Colts re-signed Sermon to a new contract.