USC

USC may refer to:

United States

 * Universidad del Sagrado Corazón, Santurce, Puerto Rico
 * University of South Carolina, Columbia, South Carolina
 * University of South Carolina System, a state university system of South Carolina
 * University of Southern California, Los Angeles, California
 * University of Southern Colorado, Pueblo, Colorado
 * Upper St. Clair High School, Upper St. Clair, Pennsylvania
 * Utica School of Commerce, a defunct business college in Utica, New York

Worldwide

 * Shih Chien University, Taipei and Kaohsiung, Taiwan
 * Sichuan University, Chengdu, China
 * Ullapara Science College, Rajshahi Division, Bangladesh
 * University of San Carlos, Cebu City, Philippines
 * University of Santiago de Compostela, Santiago de Compostela, Spain
 * University of Science and Culture, Tehran, Iran
 * University Senior College, a year 11 and 12 school in Adelaide, South Australia
 * University of South China, Hengyang, China
 * University of the Southern Caribbean, Maracas Valley, Trinidad and Tobago
 * University of the Sunshine Coast, Queensland, Australia

Government

 * United Somali Congress (1987–2004), a former major rebel organization
 * United States Code, the official code of United States federal law
 * United States Congress, the law-making body of the United States government
 * Universal Social Charge, an income tax in Ireland
 * Utility Stores Corporation, a Pakistani state-owned store chain

Law enforcement

 * Ulster Special Constabulary, a former reserve police force in Northern Ireland
 * United States Constabulary (1946–1952), the security force of the U.S. Occupation Zone of West Germany

Sports

 * UEFA Super Cup, an annual association football super cup match
 * United Soccer Coaches, a United States organization
 * United SportsCar Championship, a racing series in the United States and Canada
 * Unity Sporting Club, an association football (soccer) club in Wenchi, Ghana
 * USC Lion Soccer Club, an association football (soccer) club in Adelaide, Australia, playing in the South Australian Amateur Soccer League

Miscellaneous

 * USC (clothing retailer), in the United Kingdom
 * USC Canada, a Unitarian development organization promoting agricultural biodiversity
 * Heckler & Koch USC, a semiautomatic submachine gun
 * Ubuntu Software Center, a discontinued software management system
 * Uchinoura Space Center, a JAXA space vehicle launch facility
 * Unified Soil Classification System, used in engineering and geology
 * United Shipbuilding Corporation, in Russia
 * United States customary units, a system of measurement
 * WWE United States Championship, a wrestling event