Uracil/thymine dehydrogenase

Uracil/thymine dehydrogenase (, uracil oxidase, uracil-thymine oxidase, uracil dehydrogenase) is an enzyme with systematic name uracil:acceptor oxidoreductase. This enzyme catalyses the following chemical reaction


 * (1) uracil + H2O + acceptor $$\rightleftharpoons$$ barbiturate + reduced acceptor
 * (2) thymine + H2O + acceptor $$\rightleftharpoons$$ 5-methylbarbiturate + reduced acceptor

Uracil/thymine dehydrogenase forms part of the oxidative pyrimidine-degrading pathway in some microorganisms.