Wyoming Highway 221

Wyoming Highway 221 was a 1.84 mi east–west Wyoming State Road known as Fox Farm Road located in southeastern Cheyenne.

Route description
Wyoming Highway 221 traveled from I-25 Business/US 85/US 87 Business (South Greeley Highway) to Wyoming Highway 212 (College Avenue). Highway 221 paralleled Interstate 80 about one-half mile south of the Interstate and served residential and commercial areas. The route was decommissioned in 2009; all state route marker signs have been removed, and the route no longer appears on the Wyoming Official State Highway Map.