1921 Ohio State Buckeyes football team

The 1921 Ohio State Buckeyes football team represented Ohio State University in the 1921 Big Ten Conference football season. The Buckeyes compiled a 5–2 record while outscoring opponents 110–14. The 14 points allowed came in Ohio State's only losses. The Buckeyes' 1921 loss to remains their last loss to a team from the state of Ohio.

Coaching staff

 * John Wilce, head coach, ninth year