1960 United States presidential election in Missouri

The 1960 United States presidential election in Missouri took place on November 8, 1960, as part of the 1960 United States presidential election. Voters chose 13 representatives, or electors, to the Electoral College, who voted for president and vice president.

In the nation's third-closest race, Missouri was won by Senator John F. Kennedy (D–Massachusetts), running with Senator Lyndon B. Johnson, with 50.26 percent of the popular vote against incumbent Vice President Richard Nixon (R–California), running with United States Ambassador to the United Nations Henry Cabot Lodge Jr., with 49.74 percent of the popular vote. , this is the last election in which Osage County voted for a Democratic Presidential candidate. It also remains the most recent election in which a Northern Democrat has carried Missouri. The only subsequent Democratic nominees to carry the state have been from the South (Lyndon B. Johnson of Texas, Jimmy Carter of Georgia, and Bill Clinton of neighboring Arkansas)--although Northern Democrat Barack Obama of neighboring Illinois came very close to winning it in 2008, losing it by a razor-thin margin of 0.13 points or fewer than 4,000 votes.

A 101,000-vote margin in Kennedy's favor in St. Louis was nearly 10 times Kennedy's statewide margin.