1980–81 Albanian Cup

1980–81 Albanian Cup (Kupa e Shqipërisë) was the twenty-ninth season of Albania's annual cup competition. It began in August 1980 with the First Round and ended in June 1981 with the Final matches. The winners of the competition qualified for the 1981-82 first round of the UEFA Cup. Partizani were the defending champions, having won their eleventh Albanian Cup last season. The cup was won by Vllaznia.

The rounds were played in a two-legged format similar to those of European competitions. If the aggregated score was tied after both games, the team with the higher number of away goals advanced. If the number of away goals was equal in both games, the match was decided by extra time and a penalty shootout, if necessary.

First round
Games were played on August & September 1980*


 * Results unknown

Second round
In this round entered the 16 winners from the previous round. First and second legs were played in January 1981.


 * }

Quarter-finals
In this round entered the 8 winners from the previous round.


 * }

Semi-finals
In this round entered the four winners from the previous round.


 * }

Finals
In this round entered the two winners from the previous round.


 * }