1991 Louisville Cardinals football team

The 1991 Louisville Cardinals football team represented the University of Louisville as an independent during the 1991 NCAA Division I-A football season. Led by seventh-year head coach Howard Schnellenberger, the Cardinals compiled a record of 2–9. The team played their home games in Cardinal Stadium in Louisville, Kentucky.

NFL Draft
The following Cardinal was selected in the 1992 NFL Draft after the season.