2010 FC Spartak Moscow season

The 2010 FC Spartak Moscow season was the club's 19th season in the Russian Premier League season.

Spartak finished the season in 4th place, qualifying for the 2011–12 UEFA Europa League Play-off rounds. After entering the 2010–11 UEFA Champions League at the group stage, Spartak finished third behind Chelsea and Marseille, progressing to the Round of 32 of the 2010–11 UEFA Europa League due to take place during the 2011–12 season. In the 2010–11 Russian Cup, Spartak progressed to the Round of 16, also taking place during the 2011–12 season.

Russian Cup
The Round of 16 took place during the 2011–12 season.

Appearances and goals

 * colspan="16"|Players away from the club on loan:
 * colspan="16"|Players away from the club on loan:


 * colspan="16"|Players who appeared for Spartak Moscow but left during the season:
 * colspan="16"|Players who appeared for Spartak Moscow but left during the season:


 * }